The Museum is well posted with more than twenty signs within Fitchburg providing directions.

From the East:
- Take Rt. 2 west to exit 31B (Rt. 12 North).
- Take Rt. 12 north approximately 4 miles.
- Turn right after the Central Shopping Plaza.
- Turn left on Main Street and continue almost to the end.
- Turn right on Merriam Parkway.
- The Museum is at the end, on the right, through the stone courtyard wall.

From the South:
- Take Exit 10 (Auburn) from the Mass. Turnpike.
- Follow 290 (Worcester) to 190 North.
- Exit at Rt. 2 West.
- After 1/4 mile, exit at 31B as above.

From the west:
- Take Route 2 East to exit 25 (Route 2A/Fitchburg-Princeton).
- Follow 2A East approximately 4 miles and then, follow green signs to Fitchburg Art Museum.
- Signs will take you to Main Street in Fitchburg where you will make a left onto the westbound side of Main Street.
- Turn right onto Merriam Parkway.
- See above directions